Metoclopramide Injection, USP is compatible for mixing and injection with the following dosage forms to the extent indicated below: Physically and Chemically Compatible Up to 48 Hours Cimetidine Hydrochloride (SK&F), Mannitol, USP (Hospira), Potassium Acetate, USP (Invenex), Potassium Phosphate, USP (Invenex). For the Prevention of Postoperative Nausea and Vomiting. REGLAN Injection should be given intramuscularly near the end of surgery. The usual adult dose is 10 mg; however, doses of 20 mg may be used. Overview of Metoclopramide HCl (Reglan®) for Dogs and Cats. Metoclopramide, also known by the brand name Reglan®, is a drug commonly used for management of vomiting and gastrointestinal disorders in dogs and cats. Reglan for Dogs Overview Reglan is classified as an anti emetic drug, meaning one that works to prevent vomiting. In the case of metoclopramide HCl, the drug has a double effect. Metoclopramide (also known as Reglan (®)) is a medicine used in dogs to help relieve symptoms of reflux and stomach discomfort or to treat nausea and vomiting, particularly in those undergoing chemotherapy. reglan ® is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function (see DOSAGE AND ADMINISTRATION – Use in Patients with Renal or Hepatic Impairment). REGLAN Injection (metoclopramide injection, USP) is a clear, colorless, sterile solution with a pH of 4.5-6.5 for intravenous (IV) or intramuscular (IM) administration. Metoclopramide Dosage For Dogs: Talk To Your Vet As we’ve discussed, Metoclopramide is frequently prescribed by veterinarians to treat nausea and vomiting in dogs who are suffering from some form of gastric motility disorder.